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Primer Evaluation

Primer Sequences

>MiFsh-U_F-a
GCCGGTAAAACTCGTGCCAGC
>MiFish-U_R
CATAGTGGGGTATCTAATCCCAGTTTG

Expected Amplicon Size

MIDORI

MIDORI is a reference database of DNA sequences, which can be used for taxonomic assignments of all eukaryota mitochondrial DNA sequences.

In silico PCR Hits:

N(total)  = 132,578
N(PCR-e0) =   4,649
N(PCR-e1) =   6,222
N(PCR-e2) =   9,647
N(PCR-e3) =  15,387

☛ e: maximum number of mis-matches per primer

Taxa Composition:

Fish
---------------------------
N(Actinopteri)    =  7,355
N(Cladistia)      =     44
N(Chondrichthyes) =    191
---------------------------
N(Fish)           =  7,590

🐟 Fish List Actinopteri 🐟 Fish List Cladistia 🐟 Fish List Chondrichthyes

Not-Fish
---------------------------
N(Amphibia)       =  1,981
N(Aves)           =    690
N(Dipnoi)         =      3
N(Hyperoartia)    =     14
N(Insecta)        =      3
N(Lepidosauria)   =  2,911
N(Mammalia)       =  2,112
N(UnknownClass)   =     83
---------------------------
N(Not-Fish)       =  7,797 

Not-🐟 Fish List

⇒ Expected 12S fragment size: Amplicon (219nt) - Primer-F (21nt) - Primer-R (27nt) = 171nt

MitoFish