Evolutionary Genetics ➜ Population Genetics¶

Date: W45-W47
Lecturer: Jean-Claude Walser
Update: 19-Nov-2020

Overview¶

Welcome to the course website of Evolutionary Genetics - Population Genetics. This website is part of the course material and should help you with links, downloads, exercises and more.

Handouts¶

TU 03.11.20 - Phenotypic Variation & HWE
TH 05.11.20 - Genetic Drift
TU 10.11.20 - Ne / Non-Random Mating / Mutation / Gene Flow
TH 12.11.20 - Selection / Fst
TU 17.11.20 - Linkage Disequilibrium
TH 19.11.20 - QTL/GWAS, Network, RM

Extras:

Requirements¶

PopG¶

Download the program PopG. It is a Java application and it will run on Windows, Mac OS X, and Linux systems if you have Java installed. It is a nice application to simulate one-locus, two-allele populations to better understand the effect of natural selection, mutation, migration, and genetic drift.

HardyWeinberg - R package¶

The HardyWeinberg R package contains a nice collection of tools for exploring HW equilibrium (Hardy, 1908; Weinberg, 1908) for bi- and multi-allelic genetic marker data.

install.packages("HardyWeinberg")

learnPopGen - R package¶

LearnPopGen is a new R package by Revell (2019)[Revell-2019-Ecology_and_Evolution.pdf] for population genetic simulation. LearnPopGen can be installed directly from the Comprehensive R Archive Network, CRAN (https://CRAN.R‐project.org/package=learnPopGen).

install.packages("learnPopGen")

Assignments¶

You have to hand in a markdown or Rmarkdown based HTML report with your solutions.

➜ Deadline: 04.12.20

Solutions

Once I have received the assigments I will release the solutions. You do not have to hand in all the assignmetns together but can split it into the different chapters: HWE, Genetic Drift, Effective Population Size, and Non-Random Mating.

Reading¶

NaturalSelection (by Carolita Johnson)